Drugs that are available over-the-counter without requiring prescription are not without risk because NSAIDs prolong usage can put you at risk of heart attack, kidney disease, bleeding disorders and liver damage. If you use them for a long time without consulting a doctor, then you might be keeping yourself unknown about any hidden problem – which could be the cause of the pain. Therefore, if you are taking pain relievers frequently or for more than 10 days in a row, then it would be better if you see your doctor at the earliest.